Research Articles
Premenstrual Exacerbation (PME): Pathophysiology, Clinical Management, and Drug Development Opportunities
This article provides a comprehensive analysis of premenstrual exacerbation (PME), the cyclical worsening of underlying psychiatric disorders during the luteal menstrual phase.
Determining Limit of Quantitation (LOQ) in Hormone Assays: A Comprehensive Guide for Researchers and Developers
Accurate determination of the Limit of Quantitation (LOQ) is critical for ensuring the reliability of hormone assays in research and drug development.
Immunoassay Kits for Hormone Measurement: A Comprehensive Guide to Plasma vs. Serum Analysis for Researchers
This article provides a critical analysis for researchers and drug development professionals on the use of immunoassay kits for hormone quantification in serum and plasma.
Intermenstrual Bleeding in Research: Analytical Frameworks for Cycle Calculation and Clinical Endpoint Validation
This article provides a comprehensive framework for researchers and drug development professionals on integrating intermenstrual bleeding (IMB) into menstrual cycle calculations and clinical trial analyses.
Advancing Female Athlete Research: A Comprehensive Guide to Field-Based Hormone Detection
This article provides a foundational and methodological guide for researchers and scientists on integrating hormone detection into field-based sports research.
Optimizing Luteal Phase Progesterone Measurement: A Scientific Guide for Timing, Methodology, and Clinical Application in Reproductive Research
This article provides a comprehensive analysis of luteal phase progesterone testing for researchers and drug development professionals.
Beyond Assumptions: Establishing Standardized Hormonal Boundaries for Accurate Menstrual Cycle Phase Determination in Research
This article addresses the critical methodological challenge of defining standardized hormonal boundaries for menstrual cycle phase determination, a cornerstone for reliable research in women's health and drug development.
Beyond the 14-Day Myth: A Comprehensive Analysis of Follicular and Luteal Phase Variability in Menstrual Cycle Research
This article synthesizes current evidence on follicular and luteal phase length variability, challenging the long-held assumption of a fixed 14-day luteal phase.
Anovulatory Cycles in Athletic Women: Prevalence, Mechanisms, and Research Implications
This article synthesizes current evidence on the high prevalence of anovulatory cycles and luteal phase deficiencies in exercising females, a critical issue often masked by regular menstrual bleeding.
Validating Non-Invasive Methods for Assessing Long-Term Hormonal Exposure: A New Paradigm for Research and Drug Development
This article provides a comprehensive review of the validation frameworks for non-invasive techniques used to assess long-term hormonal tissue exposure.