Research Articles
Anovulatory Cycles in Athletic Women: Prevalence, Mechanisms, and Research Implications
This article synthesizes current evidence on the high prevalence of anovulatory cycles and luteal phase deficiencies in exercising females, a critical issue often masked by regular menstrual bleeding.
Validating Non-Invasive Methods for Assessing Long-Term Hormonal Exposure: A New Paradigm for Research and Drug Development
This article provides a comprehensive review of the validation frameworks for non-invasive techniques used to assess long-term hormonal tissue exposure.
Validating Predictive Models for Final Adult Height in Growth Hormone-Treated Children: A Research and Clinical Perspective
This article synthesizes current research on the validation of predictive models for final adult height in children undergoing growth hormone (GH) treatment.
Combating Waning Efficacy in Long-Term Growth Hormone Therapy: Mechanisms, Predictive Modeling, and Novel Formulations
This article synthesizes current research and future directions for managing the progressive decline in growth velocity observed during long-term growth hormone (GH) therapy.
Long-Term Somatic and Bone Health Outcomes of Puberty Suppression in Transgender Youth: A Scientific Review for Researchers and Drug Developers
This article synthesizes current evidence on the long-term effects of gonadotropin-releasing hormone analogues (GnRHa) on somatic growth and bone health in transgender adolescents.
Validating the Carolina Premenstrual Assessment Scoring System (C-PASS): A New Standard for PMDD Diagnosis in Research and Drug Development
This article provides a comprehensive analysis of the Carolina Premenstrual Assessment Scoring System (C-PASS), a standardized protocol for diagnosing DSM-5 Premenstrual Dysphoric Disorder (PMDD).
Parallelism Recovery Assay Validation in Hormone Measurement: Principles, Methods, and Best Practices for Robust Bioanalytical Data
This article provides a comprehensive guide to parallelism recovery assay validation, a critical process for ensuring the accuracy and reliability of hormone measurements in biological matrices.
Neuroendocrine Profiles Compared: Oral Contraceptives vs. Naturally Cycling Women in Biomedical Research
This article synthesizes current research on the distinct neuroendocrine profiles of oral contraceptive (OC) users and naturally cycling (NC) women, a critical consideration for drug development and clinical research.
Achieving Analytical Precision: Setting Variability Goals for Robust Hormone Assay Validation
This article provides a comprehensive framework for researchers, scientists, and drug development professionals on establishing analytical variability goals for hormone assay validation.
Multilevel Modeling with Random Effects for Longitudinal Data in Biomedical Research: From Foundational Concepts to Clinical Applications
This article provides a comprehensive guide to multilevel modeling (MLM) with random effects for the analysis of longitudinal data in biomedical and drug development research.